Medicinal Chemistry

Videti, a leading contract research and development organization (CRDO) in Hyderabad, provides comprehensive medicinal chemistry services that drive drug discovery by optimizing compounds to effectively target disease-related proteins or receptors. As a contract research organization, Videti leverages advanced computational tools such as in-silico modelling and virtual screening to accelerate discovery by predicting molecule-target interactions with high precision.

Overall, Videti’s medicinal chemistry services bridge early discovery and clinical development, optimizing compounds for safety, efficacy, and successful progression through clinical trials.

CRO Services In Hyderabad

● Hit-to-Lead Development & Lead Optimization

Hit-to-Lead (H2L) development transforms initial screening hits into refined leads with improved potency, selectivity, and drug-like properties. This involves structure-activity relationship (SAR) studies to optimize biological activity and physicochemical traits, along with early ADME and toxicity profiling to assess viability.

Lead Optimization (LO) further refines these leads to enhance potency, selectivity, pharmacokinetics, and safety. It includes detailed in vivo testing and advanced ADME/toxicology studies, aiming to produce drug candidates with better efficacy, stability, bioavailability, and reduced side effects for clinical trials.

● Chiral Molecules & Complex Heterocycles

Chiral Molecules exist as mirror-image enantiomers that can have different biological effects. Controlling chirality is vital in drug design to maximize efficacy and safety by selecting the therapeutically active enantiomer.

Complex Heterocycles are rings containing atoms like nitrogen, oxygen, or sulfur alongside carbon. These versatile structures enhance interactions with biological targets and are key components in many drugs, including antibiotics, antivirals, and anticancer agents.